… cytogenetics with single nucleotide polymorphism arrays can improve the diagnostic yield and identify prognosis more precisely in myelodysplastic syndromes

Y Qin, H Zhang, L Feng, H Wei, Y Wu, C Jiang… - Annals of …, 2022 - Taylor & Francis
Single-nucleotide polymorphism arrays (SNP-A) karyotyping … progression to acute myeloid
leukaemia (AML). Diagnosis and … CN-LOH as either the sole abnormality or as a concurrent …

Trisomy 8 in acute myeloid leukemia

AL Hemsing, R Hovland, G Tsykunova… - Expert review of …, 2019 - Taylor & Francis
… with chromosome 8 specific probes and by array-based copy … number analysis with
single-nucleotide polymorphism (SNP)-… in sole trisomy 8 and other karyotypes involving and extra …

[HTML][HTML] … simultaneous detection of both gene mutations and large chromosomal abnormalities in patients with myelodysplastic syndromes (MDS) and related myeloid …

…, A Sanjuan-Pla, MA Sanz, G Sanz, F Sole… - Cancers, 2021 - mdpi.com
… include abnormalities of chromosome 7, trisomy 8 and 21, −… karyotype might lead to an
inadequate estimation of the prognostic risk. Single-nucleotide polymorphism (SNP) array-based

Refined cytogenetic IPSS‐R evaluation by the use of SNP array in a cohort of 290 MDS patients

I Scarpelli, VB Stalder, G Tsilimidos… - … , Chromosomes and …, 2023 - Wiley Online Library
trisomy 8 was identified in nine cases as the sole aberration. … karyotype, five resulted in
a discordant cytogenetic IPSS-R resulting in a downgraded cytogenetic IPSS-R array-based

Cytogenetic and Genetic Advances in Myelodysplasia Syndromes

M Bendari, N Khoubila - Cytogenetics-Classical and Molecular …, 2021 - books.google.com
chromosome 5q and 7q, trisomy 8, and complex karyotypes. New genomic technologies have
been developted, like single-nucleotide polymorphism … by array-based karyotyping and/or …

[HTML][HTML] Delineation of molecular lesions in acute myeloid leukemia patients at diagnosis: integrated next generation sequencing and cytogenomic studies

SM Papuc, A Erbescu, D Cisleanu, D Ozunu, C Enache… - Genes, 2021 - mdpi.com
… and molecular cytogenetics, array-based comparative genomic … from gross chromosomal
anomalies to single nucleotide variants… missed by routine classical karyotyping (eg, KMT2A and …

[HTML][HTML] Cytogenomics Conference 2019

M ROCCHI-President, C HAFERLACH, D KOTZOT… - Molecular …, 2019 - Springer
… of chromosome banding, single nucleotide polymorphism (SNP… impact in karyotype
reorganization and chromosome evolution… myelodysplastic syndrome and acute myeloid

Chromosomal microarray analysis is superior in identifying cryptic aberrations in patients with acute lymphoblastic leukemia at diagnosis/relapse as a single assay

C Chen, EYH Heng, AST Lim, LC Lau… - International Journal …, 2019 - Wiley Online Library
Acute lymphoblastic leukemia karyotypes correlate well with … microarray analysis (CMA),
initially utilizing the array-based … probes and single nucleotide polymorphism (SNP) probes …

[HTML][HTML] Next generation cytogenetics in myeloid hematological neoplasms: Detection of CNVs and translocations

M Chicano, D Carbonell, J Suárez-González, S Lois… - Cancers, 2021 - mdpi.com
… only by cytogenetics (mainly trisomy 8), and another eight only … of normal karyotype (3/12)
or not available karyotype (3/12). … platelet disorders with propensity to acute myeloid leukemia […

The complex karyotype in hematological malignancies: a comprehensive overview by the Francophone Group of Hematological Cytogenetics (GFCH)

F Nguyen-Khac, A Bidet, A Daudignon… - Leukemia, 2022 - nature.com
… Yunis et al. reported that in myelodysplastic syndromes, the … to acute myeloid leukemia (AML)
in the current IPSS-R [5, 8, 10]. … can be detected by single-nucleotide polymorphism (SNP) …